immunology
【紹介文献】 "cis interaction of CD153 with TCR/CD3 is crucial for the pathogenic activation of senescence-associated T cells" Fukushima Y, Sakamoto K, Matsuda M et al., Cell Reports 40, 111373, September 20, 2022. https://www.sciencedirec…
【紹介文献】 Selective inhibition of miRNA processing by a herpesvirus-encoded miRNA Hennig, T. et al., 2022, Nature 605, 539-544 www.nature.com 【発表概要】 今回のサイエンスカフェではウイルスmiRNAによるmiRNAプロセシングの阻害機構について…
【紹介文献】 BT7480, a novel fully synthetic Bicycle tumor-targeted immune cell agonist(Bicycle TICA) induces tumor localized CD137 agonism Hurov et al., 2021, Journal for immunotherapy of cancer, 9(11). jitc.bmj.com 【発表概要】 今回のサ…
【紹介文献】 Erythroid mitochondrial retention triggers myeloid-dependent type I interferon in human SLE Caielli et al., 2021, Cell, 184, 1-16 www.sciencedirect.com 【発表概要】 赤血球では細胞内小器官は成熟に伴って除去されますが、全身性エ…
【紹介文献】 Shimokawa et al., Nature Communications 2020 Apr 22;11(1):1922. “CD8 + Regulatory T Cells Are Critical in Prevention of Autoimmune-Mediated Diabetes” 「CD8 +陽性制御性T細胞は自己免疫惹起一型糖尿病の予防に重要」 www.nature.com …
【紹介文献】 Hirota et al., Immunity. 2018 Jun 19; 48(6): 1220–1232.e5. "Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis" https://www.cel…
