2021-07-01から1ヶ月間の記事一覧
【紹介文献】 Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders Science 15 Jan 2021:Vol. 371, Issue 6526, pp. 265-270 science.sciencemag.org 【発表概要】 今回のサイエンスカフェでは、「老化細胞の生存戦略」と…
Multi-functionalization of all protein by copying and pasting a cyclic peptide 【紹介文献】 "Lasso-grafting of macrocyclic peptide pharmacophores yields multi-functional proteins" Emiko Mihara et al, Nat Commun. 2021 Mar 9;12(1):1543. doi:…
Does APOE4 increase AD risk via LOF or GOF, and what types of cells are involved? 【紹介文献】 Neuronal ApoE upregulates MHC-I expression to drive selective neurodegeneration in Alzheimer's disease Zalocusky KA et al., Nat Neurosci. 2021 J…
Establishment of the novel lung-on-a-chip 3D model 【紹介文献】 Reversed-engineered human alveolar lung-on-a-chip model Di Huang et al., PNAS, May 11, 2021, 118 (19) www.pnas.org 【発表概要】 創薬における革新的なツールとして、臓器チップ (o…
